The Geistlich Bio-Oss Pen is a pre-filled syringe that contains Geistlich Bio-Oss granules, which are the leading natural bone substitute for bone grafting. These granules are chemically and structurally comparable to human bone minerals, ensuring optimal biofunctionality for vascularization and the formation of new bone. He Geistlich Bio-Oss Pen® apart is its convenient and easy-to-use applicator. It guarantees the correct consistency of the granules, making it easier to access even hard-to-reach areas of the mouth. Additionally, it reduces spillage and waste, ensuring efficient and precise application. The Geistlich Bio-Oss Pen comes in two variants: one pre-filled with small (0.25–1 mm) granules and another with large (1–2 mm) granules. The small granules are recommended for small defects and autogenous graft contouring, while the large granules are ideal for larger augmentations and sinus floor elevation. With just three simple steps—hydrate, change tips, and apply—the Geistlich Bio-Oss Pen® is ready to use. It has gained a reputation for its reliability and effectiveness in bone regeneration procedures.